The End of Migraines: 150 Ways to Stop Your Pain

3rd Edition, Updated 2026 — includes 5 new migraine drugs, a promising new supplement, and expanded chapters with the latest treatment advances.

Are you tired of migraine treatments that don't work? Frustrated by doctors who give up too easily? Overwhelmed by conflicting advice about supplements, medications, and lifestyle changes?

The End of Migraines is your evidence-based roadmap to relief, written by a headache neurologist with nearly four decades of experience treating migraine.

WHAT MAKES THIS BOOK DIFFERENT

Over 150 treatment options, ranked and evaluated

Both prescription medications and non-drug approaches

Written by a migraine sufferer who understands your pain personally

Reading The End of Migraines is like having access to a migraine treatment encyclopedia and your favorite doctor, simultaneously — that wise specialist with decades of experience who gives you a compassionate straight answer. — Book reviewer

NON-DRUG TREATMENTS (75+ OPTIONS)

Which supplements actually work; dietary triggers beyond the obvious; neuromodulation devices; mind-body therapies; physical approaches.

PRESCRIPTION MEDICATIONS (50+ OPTIONS)

CGRP inhibitors; Botox; traditional preventives; acute treatments: triptans, NSAIDs, gepants; unusual drugs.

SPECIAL TOPICS

Menstrual migraine; medication overuse; creating your personalized treatment plan; environmental triggers, sleep, stress.

ABOUT THE AUTHOR

Dr. Alexander Mauskop is a board-certified neurologist and Professor of Clinical Neurology. He founded the New York Headache Center in 1987, pioneered Botox for migraine, and participated in FDA approval studies for Botox and other migraine medications. He has trained over 300 physicians worldwide in advanced headache treatment, led groundbreaking research on magnesium, and been named a Castle Connolly Top Doctor for 27 consecutive years.

PRAISE FROM LEADING NEUROLOGISTS

Dr. Mauskop has treated thousands of patients with migraine during decades of clinical experience. He is a gifted educator and this volume showcases his extraordinary ability to condense evidence and clinical observation into pithy analysis and practical suggestions.
— Russell K. Portenoy, MD, Professor of Neurology, Albert Einstein College of Medicine

Knowledge is power and migraine patients will be empowered with knowledge after reading The End of Migraines. Not only will migraineurs benefit from this book, but so will neurologists!
— Orrin Devinsky, MD, Professor of Neurology, Neurosurgery, and Psychiatry, NYU Grossman School of Medicine

This is a highly readable and practical guide which will be valuable to all people battling migraine, as well as their family and friends.
— Morris Levin, MD, Professor of Neurology, Director of the Headache Center at UCSF Medical Center

Dr. Mauskop employs his extensive clinical experience with historical anecdotes, scientific references and a dash of humor.
— Thomas N. Ward, MD, Editor-in-Chief, Headache journal

WHAT READERS ARE SAYING

Contains a wealth of information presented in a comprehensive, well-organized, easy-to-read manner.

Dr. Mauskop offers a wide array of treatment options all in one book. The rating system he uses for each treatment is very helpful.

It is encyclopaedic in its scope and very easy to read and digest.

A refreshingly pragmatic perspective with interesting research, historical context, and practical solutions.

The Kindle version includes clickable hyperlinks to peer-reviewed research studies, medical journal articles, and supplemental resources.