{"product_id":"b00ehpzoby","title":"New Gold-Catalyzed Reactions and Applications for the Synthesis of Alkaloids (Springer Theses)","description":"\u003cp\u003eAna Escribano Cuesta's thesis presents a detailed study of the inter- and intramolecular reactions of carbonyl compounds with 1,6-enynes using gold (I) complexes. An important part of the work involved streamlining the variables that allow the selective synthesis of different products such as tricyclic compounds, dihydropyrans, 1,3-dienes or cyclobutenes. The second chapter highlights the importance and difficulties in synthesising a cyclobutene subunit and the author includes a detailed description of how the products were prepared. The final chapter outlines the synthesis of lundurines using methodology developed by the author's research group for intramolecular gold-catalyzed cyclization of indoles with alkynes. The lundurine products developed in this work show significant in vitro cytoxicity toward B16 melanoma cells. The work in this thesis has led to a number of publications in high-profile chemistry journals.\u003c\/p\u003e","brand":"ANT","offers":[{"title":"Ebook","offer_id":52817508237528,"sku":"YSL31188","price":47.52,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0835\/3356\/2072\/files\/619dfqhcC4L._SY1500.jpg?v=1793085318","url":"https:\/\/www.bookmebay.com\/products\/b00ehpzoby","provider":"BookMebay","version":"1.0","type":"link"}